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S4 class to store ToxPi result calculation parameters

Arguments

rank.ties.method

Passed to rank.ties.method slot

negative.value.handling

Passed to negative.value.handling slot

Details

If more than one value is passed to TxoResultParam scalar options, e.g. rank.ties.method, only the first value is kept.

The rank.ties.method slot is passed to base::rank for calculating the ranks of observations, with the highest-scoring observation having the rank of 1.

negative.value.handling indicates how to handle negative values in the inputs. The ToxPi algorithm originally intended to accept non-negative potency values; the GUI, therefore, treats negative values in the input as missing. By default, txpCalculateScores keeps negative values (negative.value.handling = "keep"). To replicate the GUI behavior, users can set negative.value.handling = "missing".

Slots

rank.ties.method

Character scalar, method used to calculate score ranks passed to base::rank

negative.value.handling

Character scalar, how negative values are handled, see details